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DocofHealth IGF-1, Colostrum and Cancer Scares— THE FINE ART OF SEPARATING BAD GUYS FROM INNOCENT BYSTANDERS e’ve been following the controversy over the powerful anabolic peptide compound, insulin-like growth factor-1, which is produced in the liver in response to growth hormone. Some highly respected medical experts have stated their belief in health magazines, books and in consumer alerts that high circulat- ing levels of free IGF-1 in the human body contribute to cancer. IGF-1 is a marker for levels of growth hor- mone in the human body, and growth hor- mone has been shown to be a potent rejuvenating tool, whether used pharmaceuti- cally or homeopathically. In addition, IGF-1 is a key component of the longevity superfood, colostrum. W SEPARATING ARTIFACTS FROM CAUSES According to Alfred E. Fox, Ph.D., one of the world’s leading experts on dairy prod- ucts and IGF-1, there is no question that there is an increased circulating level of IGF-1 in patients with prostate, breast, col- orectal, and lung cancers and some leukemias. But you have to go further into the stud- ies to unravel the mystery. You see, blaming IGF-1 for cancer might be a lot like blaming innocent bystanders to a robbery just because they are in the area. The effects of IGF-1 on the cells, which include cell growth, survival and transforma- tion, are mediated through its interaction with IGF-1 receptors on cell surfaces. Many additional regulating substances in both nor- mal and disease processes further modulate the interaction of IGF-1 with its receptors. Studies from the National Institutes of Health have shown that in malignant dis- ease there are more than enough IGF-1 receptors on cell surfaces, but the ability of these receptors to interact with IGF-1 is significantly reduced. NIH research has also been able to demonstrate that the most frequently mutated gene in human cancer, p53, lowers the ability of the IGF-1 recep- tors to bind IGF-1 and function. The Doctors’ Prescription Says Fox, "The evidence shows that the underlying cause for elevated levels of First-milking colostrum such as Immune Tree IGF-1 seen in cancer is related to a is a rich source of many health-promoting compouds. cascade of events that began with an alt- Only unadulterated, first-milking products without eration of basic genetic information and their fat removed are likely to be rich in these immune, growth and metabolic factors. Some culminated in an impaired functioning companies de-fat their colostrum products, not being of the IGF-1 receptors on the surface of sensitive to the fact that fat is not only a carrier of the cells. In this case, since IGF-1 does the most biologically active components in colostrum not have operating, functional receptors but also that fat protects these compounds during to interact with, it naturally backs up in processing. Immune Tree is true first-milking the circulation as a manifestation of the colostrum—a whole food that is only minimally disease process." Indeed, it might even processed. We have found health-conscious be that we have to bring the cell IGF-1 consumers get great results from this product. receptors back to functional health as While adults can use colostrum as both a capsule, part of the healing process. IGF-1 is powder or pineapple lozenge, children tend to love clearly an innocent bystander, Dr. Fox the strawberry chewable. Immune Tree is widely explains. available through health distributers nationwide. True first-milking colostrum is a power- Call (877) 295-1269 to find a vendor or go to an ful immune health food that will benefit online vedor at www.dockofhealth.com. so many adults and children. First- milking colostrum is rich in immune antibodies that support our health against so many common path- Immune Tree ogens that throughout the colostrum products world it is considered a are available at health healthy natural part of the food stores and diet, especially for rejuvena- natural health centers. tion. We especially like the strawberry chewable colostrum tablets from Immune Tree, which are the ones our own Healthy Living children prefer. These seem to be one of the keys to their strong immune health. REFERENCES Butler, A.A., et al. “Stimulation of tumor growth by recombinant insulin-like growth factor-I (IGF-1) is dependent on the dose and level of IGF-1 receptor expression.” Cancer Res, 1998; 58(14):3021-7. Grimberg, A. & Cohen, P “Role of insulin-like growth factors and . their binding proteins in growth control and carcinogenesis.” J Cell Physiol, 2000;183(1):1-9 Werner, H., et al. “Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor-I receptor gene.” Proc Natl Acad Sci USA, 1996;93(16):8318-23. 4 The Doctors’ Prescription for Healthy Living / Volume 9, Number 10
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